Introduction. Prohormones are precursors, or ‘one step away’ to a hormone. They, in themselves, may not provide hormonal benefits, but can easily be converted in to the required type of hormones, aided by various enzymes present in the body. This in essence, clearly differentiates them from steroids, hormone like substances. Prohormones are best suited for small molecules based hormones, such as testosterone, which require single step conversion to stabilize the hormone levels in the body. Proinsulin and Pro-opiomelanocortin are a couple of naturally produced prohormones in the body. (1)
Over the decades, most athletes and body builders have preferred the use of prohormones to that of steroids. Prohormones help them get the reputed pumping up benefits of anabolic steroids, such as testosterone, without any of its side effects and risks.
Legal Status of Prohormones. The Food & Drug Administration (FDA) in the United States now classifies prohormones supplements as anabolic steroids only, instead of dietary supplements earlier. Therefore, now even the prohormones are considered illegal. They are categorized under ‘Controlled Substances,’ resulting in ban on their selling and use. Their acceptance remains debatable, as their long term effects have not been thoroughly studied. (2)
Sources of Prohormones. Prohormones supplements are usually available in two forms, liquid, and tablets, to replenish the body with the required type and level of prohormones. They are no more easily available as over the counter drugs in pharmaceutical shops. If extremely required, they should be taken under strict medical consultation.
Benefits of Prohormones.
Performance Boost. Prohormones help increase the body’s performance by reducing the body fat, and increasing the muscle mass & stamina.
Muscle Power. Prohormones help enhance the lean muscles mass, thereby enhancing their size, strength, and endurance.
Reduced Recovery Time. Prohormones help increase the male performance boosting hormone, testosterone, levels in the body, resulting in quick recovery, and several prolonged, performance packed sessions.
Fat Loss. Prohormones help induce fat loss from the body, resulting in lean muscle mass.
Hormone Replacement Therapy (HRT). Some select prohormones are also used as an alternative option in HRT.
Side Effects of Prohormones.
Liver Problems & Hypertension. The introductory prohormones, such as Androstenidione (1996), 4-AD, 1-AD (1989), & M-1T (2003), were good in building muscle power and strength, but were detrimental to the liver and also led to high blood pressure. Soon, the evolved versions of prohormones came out, and the current generation prohormones are the safest till now with lesser side effects than their earlier issues. This has been achieved by doing away with the process of altering the chemical structure of the prohormones.
Sexual Complications. Most of the prohormones are precursors to more than one hormone. For instance, Androstenedione (Keto group) is a precursor to Testosterone (hydroxyl group), but unfortunately is also a precursor to estrone. Estrone is an estrogenic hormone causing adverse estrogenic effects in men, line with the illegal anabolic steroids, such as gynecomastia (feminized swelling of the nipples).
Miscellaneous. Other side effects of prohormones include acne, hair loss (male pattern baldness), and breast tissue enlargement, prostrate swelling, stressed up liver, and high cholesterol levels.
Designer Anabolic Control Act of 2014 What it Means to Prohormones
The Designer Anabolic Steroid Control Act of 2014 has now been enacted after being signed by the president, on Dec 18, 2014. However the same was introduced with necessary amendments written, on May 29, 2014. (3)
The core aim of the bill is to expand the list of anabolic steroids (20-25 steroids which were previously ignored by CSA) regulated by Drug Enforcement Administration in order to stop the trade of false labeled steroids bragging to increase muscles and more and are marketed in the form of dietary supplement and more.
Adding the above meaning to the bill, “This bill would help prevent the sale of falsely labeled steroids and punish those who seek to profit from them,” said Sen.
“The DEA needs to be able to act faster and have better enforcement tools to prosecute those that develop and falsely market anabolic steroids as safe products,” Hatch said.
The bill was successfully led to pass by The Council of Responsible Nutrition (CRN)-the leading trade association for the dietary supplement and food functional industry, and is set to be beneficial for consumers as well as responsible companies, both. By empowering DEA with new tools and authorities to identify and act on the trade of illegal drugs being marketed and sold in the form of new designer anabolic steroids, as a dietary supplement.
In general an anabolic steroid is a synthetic steroid hormone producing effects similar to testosterone and promotes growth of muscles. And according to the act an anabolic steroid is any drug or substance which ‘has been created or manufactured with the intent of producing a drug or other substance that either – (a) promotes muscle growth; or (b) otherwise causes a pharmacological effect similar to that of testosterone; or (ii) the drug or substance has been, or is intended to be, marketed or otherwise promoted in any manner suggesting that consuming it will promote muscle growth or any other pharmacological effect similar to that of testosterone’
However the exemption to this is that the substance will not be treated as an illegal anabolic steroid if it is:
• A herb or other botanical;
• A concentrate, metabolite, or extract of, or a constituent isolated directly from, an herb or other botanical; or
• A combination of 2 or more substances described in item (aa) or (bb);
• A dietary ingredient for purposes of the Federal Food, Drug, and Cosmetic Act (21 U.S.C. 301et seq.); and
• Not anabolic or androgenic.
However, certain more substances such as Oestrogens, progestins, corticosteroids, and dehydroepiandrosterone, are also in the list of exempted substances.
From our point of view, here are the things included in the legal anabolic steroid or one can say elements not considered as designer anabolic steroids:
- Progestins like 17-ProAndro, pBOLD, and 6-Mass
- DHEA such as M1D Andro and Androgro-17
- Nor Anabolic and Derived from Plant Such as EpiAndro
- Structurally Different Substance and Nor Anabolic like 3,5Diene-Dione in FormXT
- And here is the list of hormones one can assume as possibly legal to buy after the act has been enacted:
- 1-dehydroepiandrosterone (1-Andro, 3b-Hydroxy-Androst-1ene-17one)
- 4-dehydroepiandrosterone (4-Andro, 3b-Hydroxy-Androst-4ene-17one)
- Epiandrosterone (3b-Hydroxy-Androstane-17one)
The bill is not only limited to regulate the sale of illegal steroids and hormones but also enforces certain hefty fines of up to $500000 on violation of the rules and regulations as explained and enacted in the bill.
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Customer Feedback on LG Science Products
I just finished the first 3 week cycle and here are the results: Competition Lifts: – Bench Press – 415 lbs RAW – Deadlift – 525 lbs RAW. Non Competition lifts: – weighted dips 200 lbs – box squats 395 lbs – skull crushers 185 lbs – Incline press 315 lbs – decline press 365 lbs – power cleans 265 lbs It usually takes me about 6-8 weeks of training to reach these. I still have 7 weeks of training left. I recover faster and am not as sore as long. I can load the bar and train heavier than ever before. I’m extremely happy with the results so far. I talked with Don earlier this week. The majority of inquiries that I get is from younger guys and I usually accrue a crowd on deadlift day when they approach me and ask questionsKeith Barrett ( retired State Trooper) – Burtonsville, Maryland
Best Way to Use LG Sciences Products
Methyl 1-D: use 4-6 capsules a day for up to 8 weeks. Use Formadrol Extreme post cycle to restor natural testosterone production. Must be 21 years old.
Formadrol Extreme: As a testosterone and libido booster, take 4 caps per day – 2 in the morning and 2 at night. As post cycle therapy after a prohormone cycle, take 4 caps per day for up to 6 weeks.
Receptor: take 3 capsules per day on an empty stomach with your cycle. preload for at least 5 days before starting the cycle.
IGH-1: take 4-6 caps before training and bedtime to increase GH release and increased anabolic effect.Should be used ideally over 8-12 weeks minimum.